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Papers of the Week

2022 Feb

Ann Transl Med



The effects of midazolam or propofol plus fentanyl on ICU mortality: a retrospective study based on the MIMIC-IV database.


Sun W, Yan Y, Hu S, Liu B, Wang S, Yu W, Li S
Ann Transl Med. 2022 Feb; 10(4):219.
PMID: 35280412.


Patients in the intensive care unit (ICU) are often under stress and fail to cooperate well with invasive treatments. Analgesia and sedation are of great significance for reducing the suffering of patients and ensuring the application and effectiveness of treatment. For better clinical choice, we aimed to explore the effect of the combination of propofol + fentanyl or midazolam + fentanyl on the short-term prognosis of hospitalized patients in the ICU.