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Papers of the Week


Papers: 5 Mar 2022 - 11 Mar 2022


Animal Studies, Pharmacology/Drug Development


2022 Mar 04


J Chem Neuroanat

Changes in dorsal root ganglion CGRP expression in mouse pinch nerve injury model:modulation by Somatostatin type-2 receptor.

Authors

Abstract

Our previous work has shown that somatostatin effectively inhibits neuropathic pain by activating its type 2 receptor (SSTR2) in the dorsal root ganglion (DRG) and spinal cord of mice. However, the underlying mechanism of this activation has not been elucidated.