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Papers of the Week

2020 Mar 09




Anti-inflammatory effects of Jingshu Keli capsule and its components on human synoviocyte MH7A cells.


Meng X, Cheng W, Zhong S, Zhang P, Qin L, Wang X
Arthroplasty. 2020 Mar 09; 2(1):7.
PMID: 35236422.


Jingshu Keli (JSKL), a traditional Chinese medicine (TCM) formula consisting of multiple active compounds, has been officially approved by National Medical Products Administration (NMPA) for treatment of cervical radiculopathy. It relieves pain, according to TCM theory, by activating blood circulation to dissipate blood stasis. The pain mainly stems from neurogenic inflammation caused by mechanical compression of the cervical nerve root. In addition, inflammation mediators also cause the development of other joint diseases, such as osteoarthritis (OA). The purpose of this paper was to evaluate the anti-inflammatory effects of JSKL and identify the biologically active herbs and compounds in vitro.