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Papers of the Week


2022 Feb 28


Biomed Pharmacother


148

Identification of prophylactic drugs for oxaliplatin-induced peripheral neuropathy using big data.

Authors

Zamami Y, Niimura T, Kawashiri T, Goda M, Naito Y, Fukushima K, Ushio S, Aizawa F, Hamano H, Okada N, Yagi K, Miyata K, Takechi K, Chuma M, Koyama T, Kobayashi D, Shimazoe T, Fujino H, Izawa-Ishizawa Y, Ishizawa K
Biomed Pharmacother. 2022 Feb 28; 148:112744.
PMID: 35240525.

Abstract

Drug repositioning is a cost-effective method to identify novel disease indications for approved drugs; it requires a shorter developmental period than conventional drug discovery methods. We aimed to identify prophylactic drugs for oxaliplatin-induced peripheral neuropathy by drug repositioning using data from large-scale medical information and life science information databases.