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Papers of the Week

2022 Jan

Ann Transl Med



Cangxitongbi capsules protect the articular cartilage in the rat knee through the long non-coding RNA HOTAIR/p38MAPK pathway.


Song X-Y, Zhao M, Zhang P, Yang L-S, Bi R-X, Xie W-P
Ann Transl Med. 2022 Jan; 10(1):23.
PMID: 35242868.


Knee osteoarthritis (KOA) is a leading cause of chronic pain and disability, and as such, it poses a significant economic burden. Traditional Chinese medicine (TCM), as well as complementary and alternative medicine, can offer safe and effective treatments for KOA. Cangxitongbi (CXTB) capsule is a Chinese patented medicine for KOA treatment and has a remarkable curative effect. This article evaluated the effects and mechanisms of CXTB in protecting joint cartilage .