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The Neck Disability Index (NDI) is a self-rated disability tool originally developed for whiplash associated disorders and validated in cervical musculoskeletal conditions. It is now commonly used to assess neck disability in migraine but it is unknown whether NDI scores relate to migraine and hypersensitivity, cervical musculoskeletal dysfunction or both. This single-blinded observational study aimed to determine whether the presence of cervical musculoskeletal dysfunction, migraine features and hypersensitivity predict NDI scores and whether alternate versions of the NDI (NDI-physical, NDI-8, NDI-5) relate more to cervical musculoskeletal dysfunction.