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Papers of the Week

Papers: 26 Feb 2022 - 4 Mar 2022

2022 Feb 28

Neurol Sci

The role of biomarkers in drug-resistant trigeminal neuralgia: a prospective study in patients submitted to surgical treatment.


Rapisarda A, Baroni S, Gentili V, Moretti G, Burattini B, Sarlo F, Olivi A, Urbani A, Montano N
Neurol Sci. 2022 Feb 28.
PMID: 35226213.


Molecular mechanisms underlying trigeminal neuralgia (TN) have been poorly understood. Recently, different biomarkers have been studied in several chronic neuropathic diseases or in neuronal damage, but their role in TN has not yet been investigated. Here, we firstly analyzed the serum levels of the neuron-specific enolase (NSE) (as an index of neuronal tissue damage) in TN patients submitted to surgical treatment. Different cytokines and interleukins related to inflammation were also studied.