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2022 Feb 23

Curr Pediatr Rev

Sweet’s syndrome: an update.


Agrawal A, Arif S H, Kumarasan K, Janjua D
Curr Pediatr Rev. 2022 Feb 23.
PMID: 35209834.


Sweet's syndrome is a serious dermatological disorder characterized by a rapid onset of tender plaques or nodules, fever, joint pain, headache, oral and genital lesions. According to the clinical features and underlying causes, Sweet's syndrome is divided into three categories i.e. classical (or idiopathic), Malignancy-associated Sweet's syndrome, and Drug-induced Sweet's syndrome. It is multifactorial in etiology, and the exact cause is still undetermined. The diagnosis can be confirmed by the routine histopathologic evaluation of skin biopsy from the lesions. The first-line treatment options are topical and systemic steroids. To identify resources for this literature review, multiple databases like Medline/PubMed, Scopus, and Google Scholar were used. The relevant information was collected from various case reports, case series, reviews, meta-analyses and large clinical trials reporting clinical description, etiology, diagnosis and management of Sweet's syndrome. The aim of this narrative review is to discuss recent understandings related to Sweet's syndrome, both in terms of clinical presentation and management approach.