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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Evaluation of the GABAA Receptor Expression and the Effects of Muscimol on the Activity of Wide Dynamic Range Neurons Following Chronic Constriction Injury of Sciatic Nerve in Rats.

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2021 Sep-Oct


Basic Clin Neurosci


http://www.ncbi.nlm.nih.gov/pubmed/35173919?dopt=Abstract


12


5

Evaluation of the GABAA Receptor Expression and the Effects of Muscimol on the Activity of Wide Dynamic Range Neurons Following Chronic Constriction Injury of Sciatic Nerve in Rats.

Authors

Evaluation of the GABAA Receptor Expression and the Effects of Muscimol on the Activity of Wide Dynamic Range Neurons Following Chronic Constriction Injury of Sciatic Nerve in Rats.
Sadeghi M, Manaheji H, Zaringhalam J, Haghparast A, Nazemi S, Bahari Z, Noorbakhsh S M
Basic Clin Neurosci. 2021 Sep-Oct; 12(5):651-666.
PMID: 35173919.

Abstract

The modality of γ-aminobutyric acid type a receptors (GABAA) controls dorsal horn neuronal excitability and inhibits sensory information. This study aimed to investigate the expression of the GABAA receptor and the effects of its agonist muscimol on Wide Dynamic Range (WDR) neuronal activity in the Chronic Constriction Injury (CCI) model of neuropathic pain.
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