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Papers of the Week

2022 Winter

Caspian J Intern Med



Sertraline-induced rectal bleeding and anal pain (a rare case presentation).


Hadinezhad P, Hosseini S H
Caspian J Intern Med. 2022 Winter; 13(1):136-138.
PMID: 35178220.


Selective serotonin reuptake inhibitors (SSRIs) have proven more problematic in terms of some side effects than the original clinical trials suggested. Sertraline may displace warfarin from plasma proteins and may increase the prothrombin time. The aim of this study was to report a rare case of the sertraline- induced severe anal pain and rectal bleeding without concurrent of taking any other drugs including non-steroidal anti-inflammatory drugs (NSAIDs).