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Papers of the Week

Papers: 12 Feb 2022 - 18 Feb 2022

2022 Feb 14

Pflugers Arch

Nobel somatosensations and pain.


Reeh PW, Fischer M J
Pflugers Arch. 2022 Feb 14.
PMID: 35157132.


The Nobel prices 2021 for Physiology and Medicine have been awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch", TRPV1 and PIEZO1/2. The present review tells the past history of the capsaicin receptor, covers further selected TRP channels, TRPA1 in particular, and deals with mechanosensitivity in general and mechanical hyperalgesia in particular. Other achievements of the laureates and translational aspects of their work are shortly treated.