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Papers of the Week

2022 Feb 10

J Pediatr Gastroenterol Nutr

Ledipasvir-sofosbuvir in Adolescents with Chronic Hepatitis C and Hematological Malignancies Undergoing Chemotherapy.


El-Sayed M H, Ebeid F ES, Zekri A-R, Massetto B, Kersey K, Zhang F, Gaggar A, Elsayed W, El-Haddad A
J Pediatr Gastroenterol Nutr. 2022 Feb 10.
PMID: 35149641.


In children with hematological malignancies, chronic HCV infection has been associated with more rapid liver disease progression and higher risk of malignancy relapse due to chemotherapy interruption. We evaluated the safety and efficacy of ledipasvir-sofosbuvir for 12 weeks in these patients.