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Papers of the Week

2021 Oct

Anesth Pain Med (Seoul)



Preoperative hyperlactatemia and early mortality after liver transplantation: selection of important variables using random forest survival analysis.


Cheong Y S, Lee S H, Lee D-K, Kim K-S, Sang B-H, Hwang G-S
Anesth Pain Med (Seoul). 2021 Oct; 16(4):353-359.
PMID: 35139616.


Generally, lactate levels > 2 mmol/L represent hyperlactatemia, whereas lactic acidosis is often defined as lactate > 4 mmol/L. Although hyperlactatemia is common finding in liver transplant (LT) candidates, association between lactate and organ failures with Acute-on-chronic Liver Failure (ACLF) is poorly studied. We searched the important variables for pre-LT hyperlactatemia and examined the impact of preoperative hyperlactatemia on early mortality after LT.