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Papers of the Week

2022 Feb 04


Analgosedation before Less-Invasive Surfactant Administration: A Systematic Review.


Tribolet S, Hennuy N, Snyers D, Lefèbvre C, Rigo V
Neonatology. 2022 Feb 04:1-14.
PMID: 35124678.


Surfactant therapy is the cornerstone of respiratory distress syndrome management. "Less-invasive surfactant administration (LISA)" is now recommended for spontaneously breathing preterm infants. Analgosedation remains controversial as 52% of European neonatologists do not use any. This systematic review aims to describe the efficacy and safety of different drugs for analgosedation during LISA.