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Papers of the Week

Papers: 29 Jan 2022 - 4 Feb 2022

Animal Studies

2022 Feb 02


Evidence of Anti-Inflammatory Effect of Transcranial Direct Current Stimulation in a CFA-Induced Chronic Inflammatory Pain Model in Wistar Rats.


Silva S P, Martins O G, Medeiros L F, Crespo P C, do Couto C A T, de Freitas J S, de Souza A, Morastico A, Cruz L A X, Sanches P R S, Caumo W, Gamaro G D, da Torres I L S, de Souza I C C
Neuroimmunomodulation. 2022 Feb 02:1-15.
PMID: 35108707.


Given that chronic inflammatory pain is highly prevalent worldwide, it is important to study new techniques to treat or relieve this type of pain. The present study evaluated the effect of transcranial direct current stimulation (tDCS) in rats submitted to a chronic inflammatory model by nociceptive response, biomarker levels (brain-derived neurotrophic factor [BDNF] and interleukin [IL]-6 and IL-10), and by histological parameters.