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Papers of the Week

Papers: 29 Jan 2022 - 4 Feb 2022

Pharmacology/Drug Development

2022 Feb 01

Obstet Gynecol



Medical Cannabis for Gynecologic Pain Conditions: A Systematic Review.


Liang AL, Gingher EL, Coleman JS
Obstet Gynecol. 2022 Feb 01; 139(2):287-296.
PMID: 35104069.


The endocannabinoid system is involved in pain perception and inflammation. Cannabis contains delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which are cannabinoids that bind to endocannabinoid system receptors. A fatty acid amide called palmitoylethanolamide (PEA) enhances endogenous cannabinoids. Given that use of medical cannabis is increasing, we sought to characterize patterns of cannabis use for gynecologic pain and its effectiveness as an analgesic.