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Papers of the Week
Dexamethasone does not provide additional clinical analgesia effect to local wound infiltration: A comprehensive systematic review and meta-analysis.
Abstract
Although use of dexamethasone as an adjunct agent is associated with alleviating pain and prolonging analgesic duration in local wound infiltration (LWI), efficacy and safety of dexamethasone-infiltration have not been fully explored. The study sought to quantify the pooled effects of dexamethasone-infiltration on postoperative pain, analgesic consumption, and side-effects through a review of randomized controlled trials (RCTs).