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Drug Des Devel Ther


Less Well-Known Consequences of the Long-Term Use of Opioid Analgesics: A Comprehensive Literature Review.


Kotlińska-Lemieszek A, Żylicz Z
Drug Des Devel Ther. 2022; 16:251-264.
PMID: 35082488.


The adverse effects of short-term opioid analgesics are well known and acknowledged; however, the spectrum of the sequelae of long-term use seems less clear. Some effects may remain undetected but still have the potential to cause harm and reduce patients' quality of life.