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Papers of the Week

2021 Dec 18


Gradation of Clinical Holistic Response as New Composite Outcome to Evaluate Success in Spinal Cord Stimulation Studies for Pain.


Goudman L, Billot M, Duarte RV, Eldabe S, Rigoard P, Moens M
Neuromodulation. 2021 Dec 18.
PMID: 35088757.


The most prominent outcome measurement in the field of neuromodulation is pain relief. Nevertheless, the number of studies that rely on composite outcomes has increased. The aims of this study are twofold: (1) to evaluate which measures are important to include in a composite outcome and (2) to develop this new composite outcome to evaluate the degree of being a clinical holistic responder with a corresponding minimal clinical important difference (MCID).