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Papers of the Week


2022 Jan 28


Medicine (Baltimore)


101


4

Low dose naloxone for pruritus in systemic sclerosis: Case series and literature review.

Authors

Meridor K, Berookhim J, Levy Y
Medicine (Baltimore). 2022 Jan 28; 101(4):e28653.
PMID: 35089206.

Abstract

Pruritus is a common symptom in patients with systemic sclerosis and has a tremendous effect on the quality of life. Nevertheless, current therapeutic options are limited. The pathogenesis of pruritus in systemic sclerosis is not completely understood; however, opiate-mediated neurotransmission has been postulated to be involved.