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Papers of the Week

Papers: 22 Jan 2022 - 28 Jan 2022

Pharmacology/Drug Development

2021 Dec

Int J Spine Surg



Intradiscal Injection of Iron-Labeled Autologous Mesenchymal Stromal Cells in Patients With Chronic Low Back Pain: A Feasibility Study With 2 Years Follow-Up.


Papadimitriou N, Hebelka H, Hingert D, Baranto A, Henriksson H B, Lindahl A, Brisby H
Int J Spine Surg. 2021 Dec; 15(6):1189-1197.
PMID: 35078893.


Degeneration of the intervertebral disc is considered to be central in pain pathogenesis in patients suffering from chronic low back pain (LBP). In recent years, the injection of mesenchymal stromal cells (MSCs) into the disc to arrest or reverse the degenerative process has been proposed as an alternative therapy. The aim of the present study was to investigate the feasibility of using iron-labeled MSCs for intradiscal injection in patients with long-standing LBP.