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Papers of the Week

Papers: 22 Jan 2022 - 28 Jan 2022

2022 Jan

Pain Physician



Clinical Effects and Safety of the Use of Methylene Blue for the Treatment of Lumbar Facet Joint Syndrome.


Yu X, Zhang J, Wang M, Yang Y, Zhang W, Su D, Liao L, Yang H, Fang H, Wang X
Pain Physician. 2022 Jan; 25(1):E15-E26.
PMID: 35051142.


Lumbar facet joint syndrome (LFJS) has been suggested to be a main source of low back pain. Methylene blue (MB), an inhibitor of nitric oxide synthesis with potential analgesic and anti-inflammatory properties, has been widely applied for a variety of pain-related diseases. However, no studies have been conducted on the treatment of LFJS patients using MB.