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Papers of the Week

Papers: 22 Jan 2022 - 28 Jan 2022

Pharmacology/Drug Development

2022 Jan

Pain Physician



The Impact of Local Corticosteroid Administration on the Incidence of Post-Neurotomy Neuritis: A Prospective Investigation.


Fitzpatrick B, Hilton K, Suer M, Poliak-Tunis M, Hetzel S
Pain Physician. 2022 Jan; 25(1):E121-E126.
PMID: 35051159.


Since its adoption as a treatment for neuropathic pain in the 1960s, radiofrequency ablation (RFA) has continued to gain popularity for the management of various pain etiologies. Although RFA is considered to be a safe procedure, post-neurotomy neuritis (PNN), a neuropathic-type pain, is one of the most common side effects. Due to the increasing recognition of PNN, some providers have attempted to mitigate the risk of PNN by injecting local corticosteroids at the site of RFA following the procedure. Recent studies have generally concluded that corticosteroids do not protect against the development of PNN, however, they have been limited by their retrospective study designs and the low incidence of PNN.