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Papers of the Week

Papers: 8 Jan 2022 - 14 Jan 2022

Human Studies

2022 Jan 12

J Headache Pain



Exploring alterations in sensory pathways in migraine.


Meylakh N, Henderson LA
J Headache Pain. 2022 Jan 12; 23(1):5.
PMID: 35021998.


Migraine is a neurological disorder characterized by intense, debilitating headaches, often coupled with nausea, vomiting and sensitivity to light and sound. Whilst changes in sensory processes during a migraine attack have been well-described, there is growing evidence that even between migraine attacks, sensory abilities are disrupted in migraine. Brain imaging studies have investigated altered coupling between areas of the descending pain modulatory pathway but coupling between somatosensory processing regions between migraine attacks has not been properly studied. The aim of this study was to determine if ongoing functional connectivity between visual, auditory, olfactory, gustatory and somatosensory cortices are altered during the interictal phase of migraine.