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Papers of the Week

Papers: 8 Jan 2022 - 14 Jan 2022


Human Studies

2022 Jan 11

J Intern Med

Primary Sjögren’s syndrome: Longitudinal real-world, observational data on health-related quality of life.


Tarn J, Lendrem D, McMeekin P, Lendrem C, Hargreaves B, Ng W-F
J Intern Med. 2022 Jan 11.
PMID: 35018685.


Primary Sjögren's syndrome (pSS) is a chronic inflammatory condition, which presents with symptoms of dryness, pain, fatigue and often symptoms of anxiety and depression. Health related quality of life is significantly reduced in pSS and the direct and indirect health costs of pSS are substantial. This study aims to determine how symptom burden, disease activity and demographics associate with HRQoL longitudinally over a median of 24-month follow-up period in pSS.