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Papers of the Week

2021 Dec 01

Am J Gastroenterol


Suppl 1

P064 Association Between Crohn’s Disease (CD) and Transient IgM and IgG Immunodeficiency-Diagnostic and Management Challenges.


Rabello I M, Lopes S T, Magro D, Lahan-Martins D, Trevisan M, de Pinho Junior A, Cabral V, Coy C
Am J Gastroenterol. 2021 Dec 01; 116(Suppl 1):S17.
PMID: 35006190.


Background: CD is an inflammatory disease that predominantly affects the gastrointestinal tract and has a progressive course. Immunodeficiencies can occur by altering different components of innate or adaptive immune responses. Such changes put the patient at greater risk for infectious diseases or non-infectious complications. Among the non-infectious complications are cancer, autoimmune diseases and gastrointestinal diseases, which should be suspected in patients with recurrent infections, with clinical, radiological or histological features of the disease are atypical or in the occurrence of an unsatisfactory response to conventional therapy.