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Papers of the Week

Papers: 8 Jan 2022 - 14 Jan 2022

Pharmacology/Drug Development

2022 Jan 06

Arthritis Rheumatol

No added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis: a cluster randomised trial.


van den Driest JJ, Schiphof D, Koffeman AR, Koopmanschap MA, Bindels PJE, Bierma-Zeinstra SMA
Arthritis Rheumatol. 2022 Jan 06.
PMID: 34989159.


To assess the effectiveness of duloxetine added to usual care for patients with chronic osteoarthritis (OA) pain. Secondary objectives were to assess cost-effectiveness and to assess whether the presence of symptoms of centralized pain alters the response to duloxetine.