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Papers of the Week


Papers: 8 Jan 2022 - 14 Jan 2022


Human Studies

PAIN TYPE:
Migraine/Headache


2022 Jan 06


J Headache Pain


23


1

Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2.

Authors

Mozafarihashjin M, Togha M, Ghorbani Z, Farbod A, Rafiee P, Martami F
J Headache Pain. 2022 Jan 06; 23(1):3.
PMID: 34991456.

Abstract

Several inflammatory and vascular molecules, and neurotrophins have been suggested to have a possible role in the development of migraine. However, pathophysiological events leading to migraine onset and transformation of episodic migraine (EM) to chronic migraine (CM) are not fully understood. Thus, we aimed to assess peripheral levels of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), vascular endothelial growth factor (VEGF), and prostaglandin E2 (PGE2) in EM and CM patients, and controls.