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Papers of the Week

Papers: 8 Jan 2022 - 14 Jan 2022

Pharmacology/Drug Development

2022 Jan 06

J Neuroinflammation



Delta opioid receptors on nociceptive sensory neurons mediate peripheral endogenous analgesia in colitis.


Mas-Orea X, Basso L, Blanpied C, Gaveriaux-Ruff C, Cenac N, Dietrich G
J Neuroinflammation. 2022 Jan 06; 19(1):7.
PMID: 34991641.


Inflammatory visceral pain is endogenously controlled by enkephalins locally released by mucosal CD4 T lymphocytes in mice. The present study aimed at identifying opioid receptor(s) expressed on nociceptive sensory nerves involved in this peripheral opioid-mediated analgesia.