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Papers of the Week


2022 Jan 06


Trials


23


1

Double-blind placebo-controlled randomized clinical trial to assess the efficacy of montelukast in mild to moderate respiratory symptoms of patients with long COVID: E-SPERANZA COVID Project study protocol.

Authors

Cordero F M, Monne S B, Ortega J A, García-Sangenís A, Puèrtolas O C, Contreras-Martos S, Muñoz G A, Escolà R M, Joué M B, Pedrós R M, Salvador-Gonzalez B
Trials. 2022 Jan 06; 23(1):19.
PMID: 34991703.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic continues to affect the globe. After 18 months of the SARS-CoV-2 emergence, clinicians have clearly defined a subgroup of patients with lasting, disabling symptoms. While big strides have been made in understanding the acute phase of SARS-CoV-2 infection, the pathophysiology of long COVID is still largely unknown, and evidence-based, effective treatments for this condition remain unavailable.