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Papers of the Week

2022 Jan 07

Infect Dis Ther

A Cross-Sectional Concept Elicitation Study to Understand the Impact of Herpes Zoster on Patients’ Health-Related Quality of Life.


Van Oorschot D, McGirr A, Goulet P, Koochaki P, Pratiwadi R, Shah S, Curran D
Infect Dis Ther. 2022 Jan 07.
PMID: 34994924.


After a chickenpox infection, the varicella zoster virus lies dormant in nerve cells and can be reactivated in later life to cause herpes zoster (HZ), also called shingles, a painful rash that may result in persistent postherpetic neuralgia (PHN). Treatment options are limited, and HZ/PHN may have substantial negative effects on health-related quality of life (HRQoL). This qualitative cross-sectional study explored the subjective patient experience and impact on HRQoL of HZ and PHN in adults aged ≥ 50 years in Canada.