I am a
Home I AM A Search Login

Papers of the Week

Papers: 1 Jan 2022 - 7 Jan 2022

Animal Studies, Pharmacology/Drug Development

2022 Jan 05

Curr Top Med Chem

Antinociceptive Effects of Aza-Bicyclic Isoxazoline-Acylhydrazone Derivatives in Different Models of Nociception in Mice.


Mota F V B, Coutinho F N, de Carvalho V M F, de Assis Correia J C, Bastos I V G A, Neto P P M, Ximenes R M, Brondani D J, de Faria A R, Marchand P, da Silva T G
Curr Top Med Chem. 2022 Jan 05.
PMID: 34986770.


In a study recently published by our research group, the compounds isoxazoline-acylhydrazone derivatives R-99 and R-123 presented promising antinociceptive activity. However, the mechanism of action of this compound is still unknown.