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Papers of the Week

Papers: 1 Jan 2022 - 7 Jan 2022

Pharmacology/Drug Development

2022 Jan 03

Eur J Pain

The glial cell’s role in antinociceptive differential effects of oxytocin upon female and male rats.


Salinas-Abarca AB, Vázquez-Cuevas FG, González-Gallardo A, Martínez-Lorenzana G, González-Hernández A, Condés-Lara M
Eur J Pain. 2022 Jan 03.
PMID: 34978727.


Sex plays a crucial role in pain processing and response to analgesic drugs. Indeed, spinal glia seems to be significant in the sexual dimorphism observed in the above effects. Recently, studies have associated oxytocin with antinociceptive effects, but these have been mainly performed in male animals; consequently, the influence of sex has been poorly explored.