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Papers of the Week

Papers: 18 Dec 2021 - 24 Dec 2021

Pharmacology/Drug Development

2021 Dec 20

BMJ Open



Study protocol for a randomised controlled trial on the effect of local analgesia for pain relief after minimal invasive sacroiliac joint fusion: the ARTEMIS study.


Hermans SMM, Nellensteijn JM, van Santbrink H, Knoef R, Reinders MK, Hoofwijk DMN, Potters JW, Movig KLL, Curfs I, van Hemert WLW
BMJ Open. 2021 Dec 20; 11(12):e056204.
PMID: 34930745.


Chronic lower back pain is a common report in the general population. A dysfunctional sacroiliac joint (SIJ) is estimated to be responsible for one in five patients with lower back pain. Minimally invasive sacroiliac joint fusion (MISJF) is a surgical procedure to treat SIJ dysfunction. During the procedure, the SIJ is stabilised by implants inserted percutaneously under fluoroscopy guidance. Postoperatively, patients often report a lot of pain, which contributes to patients taking high doses of painkillers (opioids for example,) and preventing early mobilisation. In several orthopaedic procedures, intraoperative infiltration of the wound bed results in decreased consumption of analgesics, earlier mobilisation and shorter hospitalisation time. The aim of this study is to investigate the effectiveness of intraoperative SIJ infiltration with analgesia in reducing postoperative pain after MISJF.