Papers of the Week

Corticosteroids such as triamcinolone acetonide (TAA) are potent drugs administered intra-articularly as an anti-inflammatory therapy to relieve pain associated with osteoarthritis (OA). However, the ability of early TAA intervention to mitigate OA progression and modulate immune cell subsets remains unclear. Here we sought to understand the effect of early intra-articular injection of TAA towards OA progression, local macrophages and peripheral blood monocytes.