I am a
Home I AM A Search Login

Papers of the Week

2021 Dec 08

J Trace Elem Med Biol


2-Aminoethoxydiphenyl borate ameliorates functional and structural abnormalities in cisplatin-induced peripheral neuropathy.


Eroglu E, Unel C C, Harmanci N, Erol K, Ari N S, Ozatik O
J Trace Elem Med Biol. 2021 Dec 08; 70:126909.
PMID: 34902678.


Cisplatin is a platinum-derived chemotherapeutic agent commonly used in the treatment of various tumors. Ototoxicity, nephrotoxicity, and peripheral neuropathy are the most common side effects of this drug. 2-Aminoethoxydiphenyl borate (2-APB), boron- containing compound, has some protective effects against various tissue damage. The present study aimed to investigate the potential protective effects of 2-APB on in vitro and in vivo cisplatin-induced neurotoxicity.