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Papers of the Week

2021 Dec 08

J Matern Fetal Neonatal Med

The pathophysiologic, diagnostic, and therapeutic aspects of posterior reversible encephalopathy syndrome during pregnancy.


Makouei M, Hartup L A, Neuhoff B K, Boyd A R, Daftaribesheli L, Mirmoeeni S, Azari Jafari A, Godoy D A, Seifi A
J Matern Fetal Neonatal Med. 2021 Dec 08:1-9.
PMID: 34879767.


Posterior reversible encephalopathy syndrome (PRES) is a neurological condition with a wide range of symptoms, including visual disturbances, headache, vomiting, seizures, and altered consciousness. This review describes the pathophysiology of PRES, as well as the clinical, diagnostic, and therapeutic intervention during pregnancy. The gold standard for diagnosis of PRES is Magnetic Resonance Imaging (MRI), helping to differentiate it from other similar conditions. The aim of this paper is to review the principal aspects of PRES, general care, blood pressure control, and seizures prevention while avoiding potential injuries to the mother and fetus in the event of pregnancy. We concluded that PRES can be effectively treated and reversed if prompt diagnostic action is made, and adequate care is initiated.