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Papers of the Week

Papers: 27 Nov 2021 - 3 Dec 2021

Pharmacology/Drug Development

2021 Nov 24

Pain Med

A scoping review of the diurnal variation in the intensity of neuropathic pain.


Hu S, Gilron I, Singh M, Bhatia A
Pain Med. 2021 Nov 24.
PMID: 34850188.


Recent studies suggest that neuropathic pain exhibit a daily diurnal pattern with peak levels usually in the late afternoon to evening and trough in the morning hours, although literature on this topic has been sparse. This scoping review examines current evidence on the chronobiology of neuropathic pain in both animal models and in humans with neuropathic pain.