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Papers of the Week

Papers: 24 Jul 2021 - 30 Jul 2021

Pharmacology/Drug Development

2021 Jul 23

J Clin Anesth


Efficacy and adverse events of selective serotonin noradrenaline reuptake inhibitors in the management of postoperative pain: A systematic review and meta-analysis.


Schnabel A, Weibel S, Reichl SU, Meißner M, Kranke P, Zahn PK, Pogatzki-Zahn EM, Meyer-Frießem CH
J Clin Anesth. 2021 Jul 23; 75:110451.
PMID: 34311244.


Selective-serotonin-noradrenaline-reuptake inhibitors (SSNRI) might be an interesting option for postoperative pain treatment. Objective was to investigate postoperative pain outcomes of perioperative SSNRI compared to placebo or other additives in adults undergoing surgery.