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Papers of the Week

2021 Jul 22


A Clinical Feasibility Study of Spinal Evoked Compound Action Potential Estimation Methods.


Chakravarthy K, FitzGerald J, Will A, Trutnau K, Corey R, Dinsmoor D, Litvak L
Neuromodulation. 2021 Jul 22.
PMID: 34293227.


Spinal cord stimulation (SCS) is a treatment for chronic neuropathic pain. Recently, SCS has been enhanced further with evoked compound action potential (ECAP) sensing. Characteristics of the ECAP, if appropriately isolated from concurrent stimulation artifact (SA), may be used to control, and aid in the programming of, SCS systems. Here, we characterize the sensitivity of the ECAP growth curve slope (S) to both neural response (|S |) and SA contamination (|S |) for four spinal ECAP estimation methods with a novel performance measure (|S /S |).