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Papers of the Week

2021 Jul 16

Curr Pain Headache Rep



Temperature-Mediated Nerve Blocks in the Treatment of Pain.


Fishman MA, Scherer AM, Katsarakes AM, Larson L, Kim PS
Curr Pain Headache Rep. 2021 Jul 16; 25(9):60.
PMID: 34269907.


Analgesic hot and cold temperatures have been used for both conservative and ablative therapies for millennia. There are well-known locoregional neurovascular changes associated with the application of heat or ice in the literature and in practice. The oscillation between heat and cold has recently been identified as a synergistic mechanism of action with early translational results in humans.