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Papers: 10 Jul 2021 - 16 Jul 2021


2021 Jul 14

J Headache Pain



Comorbidities of primary headache disorders: a literature review with meta-analysis.


Caponnetto V, Deodato M, Robotti M, Koutsokera M, Pozzilli V, Galati C, Nocera G, De Matteis E, De Vanna G, Fellini E, Halili G, Martinelli D, Nalli G, Serratore S, Tramacere I, Martelletti P, Raggi A
J Headache Pain. 2021 Jul 14; 22(1):71.
PMID: 34261435.


Primary headache disorders are common and burdensome conditions. They are associated to several comorbidities, such as cardiovascular or psychiatric ones, which, in turn, contribute to the global burden of headache. The aim of this study is to provide a comprehensive description of the pooled prevalence of comorbidities of primary headache disorders using a meta-analytical approach based on studies published between 2000 and 2020.