- Anniversary/History
- Membership
- Publications
- Resources
- Education
- Events
- Outreach
- Careers
- About
- For Pain Patients and Professionals
We present the case of a 60-year-old patient who reported the onset of pernio-like lesions on both hands, approximately 14 days after the administration of the second dose of the Pfizer-BioNTech vaccine. Local and systemic symptoms such as pain at the injection site, asthenia and headache of mild to moderate severity also appeared following the administration of the first and second doses, and resolved within 2 days. Physical examination showed erythematous-violaceous patches and swelling on the fingers, accompanied by itching and burning sensation (Figure 1). The occasional appearance of livedo reticularis-like manifestations on the lower limbs was also referred.