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Papers of the Week

Papers: 3 Jul 2021 - 9 Jul 2021

Human Studies, Pharmacology/Drug Development

2021 Jul 05

Br J Clin Pharmacol

The dose-dependent analgesic effects, abuse liability, safety and tolerability of oral cannabidiol in healthy humans.


Arout CA, Haney M, Herrmann ES, Bedi G, Cooper ZD
Br J Clin Pharmacol. 2021 Jul 05.
PMID: 34223660.


Preclinical studies demonstrate that cannabidiol (CBD) elicits an antinociceptive response in animal models of neuropathic pain; in humans, limited data are available to support such analgesic effects. Few studies have examined CBD's analgesic effects when administered without other compounds, and little is known regarding dose-dependent effects in non-cannabis users.