I am a
Home I AM A Search Login

Papers of the Week

2021 Jun 29

J Infect Chemother

A fatal case of Exophiala dermatitidis meningoencephalitis in an immunocompetent host: A case report and literature review.



Central nervous system (CNS) infection due to Exophiala dermatitidis is rare and fatal, and primarily reported in immunocompromised patients or those with caspase recruitment domain-containing protein 9 deficiency. Herein, we describe a case of an otherwise healthy person (without underlying disease or gene deficiency) diagnosed with Exophiala dermatitidis meningoencephalitis. The patient achieved clinical remission under high-dose antifungal therapy in the first 14 months but died after 2 years of the therapy.