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Papers of the Week


2021


Biomed Res Int


2021

Minimally Invasive Embedding of Saturated MSU Induces Persistent Gouty Arthritis in Modified Rat Model.

Authors

Xu H-L, Li S-K, Xue X-A, Chen Z-Y, Hua Y-H
Biomed Res Int. 2021; 2021:6641701.
PMID: 34212036.

Abstract

Animal models are valid for research on the pathophysiological process and drug screening of gout arthritis. Intra-articular injection of monosodium urate (MSU) is the most common method, while stable MSU deposition enveloped by inflammatory cells was rarely reported.