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Papers of the Week

2021 May 03

J Clin Sleep Med

Multimodal sleep, an innovation for treating chronic insomnia: case report and literature review.


Zhang J-F, Williams JP, Zhao Q-N, Liu H, Shi W-R, Wang Y, Fang Q-W, An J-X
J Clin Sleep Med. 2021 May 03.
PMID: 34165072.


The authors present the clinical case of a 67-year-old man with severe insomnia for 5 years with an exacerbation about 1 year prior to consultation. He did not have enough concentration and energy for his daily work and developed depression and anxiety due to his excessive daytime sleepiness. During his insomniac state, a drug treatment provided partial relief, but the effects were not long-lasting. Consequently, the drug dosage increased and major side effects manifested gradually. We decided to use a completely new therapeutic strategy for this patient to improve his sleep quality and mental symptoms. In time, the patient could stop oral medications and that is multimodal sleep (MMS). After the end of MMS, the patient typically experiences improvement in sleep quality and architecture. Additionally, the dosage of hypnotics used prior to MMS is discontinued without severe withdrawal symptoms.