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Papers of the Week

2021 Jun 02

Arab J Gastroenterol

Evaluation of the role of bile acids and serotonin as markers of pruritus in children with chronic cholestatic liver disease.


Koofy N E, Yassin N, Okasha S, William H, El Akel W, Elshiwy Y
Arab J Gastroenterol. 2021 Jun 02.
PMID: 34090830.


Pruritus is an annoying symptom with an unclear pathogenesis accompanied by chronic cholestasis. This cross-sectional study was conducted to define the relationship between serum levels of presumed pruritogens (bile acids (BAs) and serotonin) and severity of pruritus in pediatric patients with chronic cholestatic liver disease.