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Papers of the Week

2021 Jun 02

Brain Res Bull

Model-based signal processing highlights bidirectional inferring between pain-evoked local field potential and spikes.


Gabrielli F, Megemont M, Dallel R, Luccarini P, Monconduit L
Brain Res Bull. 2021 Jun 02.
PMID: 34089782.


Chronic pain is associated with abnormal levels of electrical excitability of the somatosensory cortex neurons. Consequently, recording spontaneous and evoked activities by means of unitary extracellular recordings and local field potential (LFP) are key understanding the mechanisms behind such alterations. There is a growing need to highlight the relationship between spiking activity and LFP. Here, we hypothesized that LFP could be inferred from spikes under evoked conditions.