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Papers of the Week

Papers: 29 May 2021 - 4 Jun 2021

Animal Studies

2021 Jun 02

Osteoporos Int

Fracture-induced pain-like behaviours in a femoral fracture mouse model.


Magnusdottir R, Gohin S, Ter Heegde F, Hopkinson M, McNally IF, Fisher A, Upton N, Billinton A, Chenu C
Osteoporos Int. 2021 Jun 02.
PMID: 34080043.


This study is the first comprehensive characterisation of the pain phenotype after fracture using both evoked and naturalistic behaviours in adult male and ovariectomised female mice. It also shows that an anti-nerve growth factor (NGF) therapy could be considered to reduce pain after fracture surgery.