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Papers of the Week


Papers: 29 May 2021 - 4 Jun 2021


Animal Studies


2021 Jun 02


Osteoporos Int

Fracture-induced pain-like behaviours in a femoral fracture mouse model.

Authors

Magnusdottir R, Gohin S, Ter Heegde F, Hopkinson M, McNally IF, Fisher A, Upton N, Billinton A, Chenu C
Osteoporos Int. 2021 Jun 02.
PMID: 34080043.

Abstract

This study is the first comprehensive characterisation of the pain phenotype after fracture using both evoked and naturalistic behaviours in adult male and ovariectomised female mice. It also shows that an anti-nerve growth factor (NGF) therapy could be considered to reduce pain after fracture surgery.